“Why We Haven’t Cured Cancer”

Last year, SciShow, a YouTube Channel featuring Hank Green, posted a video called “Why We Haven’t Cured Cancer.” In light of recent events (David Bowie, Alan Rickman), I thought I’d share it.

Hank says that people need to stop asking about the cure for cancer because “If every tumor worked the same, we would probably by now have that magic bullet that we needed.” He also says that we have to treat cancer as if it is hundreds of different diseases.

And while it seems like no progress has been made toward treating cancer, for almost 3000 years not a single step was made. “For 3,000 years or more, this disease has been known to the medical profession. And for 3,000 years and more, humanity has been knocking at the door of the medical profession for a “cure.” – Fortune, March 1937

In 1950, the word cancer could not be published in the New York Times. Now, cancer research is in every hospital, publishing research on brand new personalized medicine and genomic therapy. Chemotherapy’s first major trial was tested on 16 children. The 10 that stayed alive for 4-6 months were considered miracles.

If you think about how hard it is now to treat cancer, look back and see how far we’ve come. Then look to the future and see how much farther we have to go.

Information from: Cancer, The Emporer of All Maladies, a Must-Read

(There is also a movie version on Netflix)

I highly recommend you watch the video.

 

Oh the Places You’ll Go

As this summer comes to a close, I am reflecting on the incredible experiences I’ve had. My book, On The Right Track, is now on sale at Books On the Common in Ridgefield and I was able to complete my research project at the Norris Cotton Cancer Institute at Dartmouth. 

I spent three weeks working in the lab with a team of people wwho were incredibly accepting of a high schoolers entering their lab. Everyone offered to help me with every step of the process and show me all of the projects they were working on. When I first arrived, I was lost. Not only did I not know what anything was or what it did, I couldn’t even find my way around. I needed help with anything and everything. But, very quickly, I started remembering things and getting the hang of processes I had only ever read about before. 

By the end of my time, I felt like a real member of the lab. I came to work early, plated my cells alone, and drugged them up using a sort of recipe card I had made up with the help of the other lab members. I set a timer and set back to wait for their incubation time to be over. 

This process became habitual and I was able to make the combinations more complicated. I factored in giving presentations and observing other people’s research into my schedule. I tried to be a sponge to the knowledge in the room. 

My mentor always said to me that if I know what the outcome is going to be, then there is nothing to test. So while I could’ve predicted what drug combinations we’re going to be effective, I could never have predicted how much other information I was going to learn about cancer treatments by testing that.

On my last day, I was given a copy of Dr. Seuss’ “Oh the Places You’ll Go.” On each page were handwritten notes from everyone at the lab. Even setting the gesture of the signed book aside, the children’s book has such immense meaning and a month later as I sit four hours away from the lab reading it again, I can’t help but share it with whoever may read this. 

“You have brains in your head. You have feet in your shoes. You can steer yourself any direction you choose.”

Update – On the Right Track

OnTheRightTrack_MEDIUM
I would like to thank everyone who has been so supportive since the release of my book. The release party was very successful and filled with family and friends from all over. Since then, I’ve received so many kind comments from readers, which has been so rewarding.

I’ve recently been interviewed by Jackie Bailey from Navigating Your Fishbowl, see here.  I am  also currently preparing to conduct research at Dartmouth’s Norris Cotton Cancer Center under the guidance of my mentor, Dr. Alan Eastman. We’ve been working together for the past 6 months, developing a plan for experimentation. We plan to spend three weeks testing different protein-targeting drugs to see which could be the most effective for treating leukemia.

Just a quick update before I leave to conduct my research, thanks for everything.

Official Book Release

OnTheRightTrack_MEDIUMThis Sunday, May 17th, 2015, John and I will be releasing our books at the Ridgefield Library from 2-4 p.m. and on Amazon.

We’re beyond excited to share our books with the public after these months of waiting and working very hard on them. My book, On The Right Track, A Student’s Memoir of Research, Advancement and Holding on to Hope, tells the story of my first year in the Science Research Program and how I began researching cancer.

I’ve learned so much about cancer, science and myself over the past two years. This opportunity to self-publish was given to me by Mr. Bryan Holmes. To him and everyone else who helped so much in this process, I can’t thank you enough. It’s been incredible to see my project grow into this.

For more information on the book, feel free to comment or contact me at jenschwartz798@gmail.com.

Preparing for Publication

After writing and rewriting, my original manuscript has grown into a final copy. With little else to do but finalize changes and convert to paperback, my book will be available for purchase on May  17, 2015.  On the Right Track, A Student’s Memoir of Research, Advancement, and  Holding  on to Hope will be available for purchase on Amazon.com.

In my story, l recall  my first year in the Science Research Program at Ridgefield High School. The year truly changed my life. I’ve discovered so  many  incredible things about cancer and  cancer research so far.  I’ve learned about new strategies for treating cancer that have the potential to change the way we think about the disease entirely.

From the research I’ve done, I can tell that research is leading cancer treatments to a place where there will be less side effects and fewer deaths.   New methods  developed in the past few years for detecting cancer have  worked  extremely well.  There are hundreds of new drugs being studied that can go into clinical trials hopefully in the next decade. Progress is being made. I promise.

I hope to provide a taste of the impact and success of cancer research thus far in my book, but also the progress that I’ve made personally.  From emailing researchers to  reading articles,  every step is leading to a better future for those affected by cancer.  Step by step, I’m taking a very long journey, but I know I’m On The Right Track.

Southern Connecticut Science and Engineering Fair 2015

Research and Innovation

This past weekend, the Ridgefield High School Science Research Program attended the 15th annual Southern Connecticut Science and Engineering Fair. Each student competed with a proposed or completed research project they’ve been working on since their first days in the course.

The effort displayed by the students was tremendous and so many were inspired by the projects they saw and the people from all over the state that they met. Students shared ideas from across the lunch table and the aisles between posters. Through the questions asked by judges and the relationships built, it was a learning experience for all.

I’d like to congratulate every student on their successes. Each and every student at the fair proved all of their efforts were aimed at innovating in the science world and enhancing life on our planet. No matter the results, everyone did an incredible job.

-Jennifer

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Why Cancer?

From the first days of my time in the Science Research Program, I began reading article after article about anything remotely biological, without focus on any particular field. I dove into researching the effects of toxins in plastics, birth defects, Down syndrome, Hemophilia and anything else that looked appealing from the title of an article.

As time progressed, I came up with the idea of studying how chemicals like BPA affect fetal development, but quickly became bored. One day in class, after scrolling through a science news site, I found a study that used nanodiamonds to increase the efficacy of chemotherapy drugs.

That single article led me to question everything I knew about cancer. I did not originally want to research a disease from personal connection but I found motivation from cancer research to continue learning. Since there are over 200 types of cancer, the most resistant cases will always struggle to find a valuable treatment option. It was the statistic proof that even cancers like breast cancer, which is most often surgical, can be treated with chemotherapy only successfully 1.5% of the time.

The resistance to treatment is what makes cancer so difficult, and finding new, unique ways to target the resistance-promoting factors is what I believe to be the future of cancer research. Any progress in this field that I can contribute to would be an immense success, as the creation of a single drug may help, even at first, dozens of patients survive longer than they might normally, which would be incredible.

Thanks,

Jennifer